Bioniq toothpaste review 2026: 20% micro HAp, checked
Bioniq Repair is a fluoride-free hydroxyapatite toothpaste from Dr. Kurt Wolff, the Bielefeld company behind Alpecin and Karex, and it is one of the few pastes in its category that prints how much hydroxyapatite it contains: 20%. That makes it easier to review than most. We read the brand's US and German product pages, both ingredient lists, its FAQ, its shipping page and its research page, then ran every study it cites through PubMed, one PMID at a time, and wrote down what each paper tested, how, on how many people, what it found, and who paid for it. Every finding below carries its source, so you can re-check any of it yourself.
Updated September 2026 · Last reviewed: 25 September 2026 · 26 min read
Disclosure: this review is by Minvelle. We make a remineralizing gum, not a toothpaste, so Bioniq is not a direct competitor, but we still have a commercial interest in this category. That is why every statement about Bioniq below is either the brand's own published text, a database record you can query yourself, or a PubMed record linked in place. Where something is our reading rather than a record, we say so.
A number on the pack, in gum form
Bioniq prints its concentration. We print ours too: 5.7 mg of nano-hydroxyapatite per 1.9 g piece of gum, one piece a day, chewed for at least 20 minutes between brushings. It sits next to your toothpaste, not in place of it.
Read the Minvelle formula30-day refund on unopened boxes
Bioniq Repair is a legitimate, fluoride-free toothpaste made by Dr. Kurt Wolff GmbH & Co. KG in Bielefeld, Germany, with 20% hydroxyapatite that the brand itself calls "micro-fine", not nano. It sells directly in the US from $16.99 for 100 mL, and its full ingredient list is public.
The one number it does not publish is a particle size. Of the 11 PubMed-indexed studies in our audit table, 9 disclose Dr. Wolff funding or Dr. Wolff employees among the authors. The best of them, an 18-month trial in 189 adults, found the paste not statistically inferior to a 1450 ppm fluoride toothpaste on new decay. And the Trustpilot page called Bioniq belongs to an unrelated supplement company, so its rating says nothing about this toothpaste.
If you are reading this because you care about seeing the number on the pack, that is the same standard we hold ourselves to. Minvelle is a chewing gum with 5.7 mg of nano-hydroxyapatite per 1.9 g piece, printed on the box, 18 pieces per box, one piece a day, chewed for at least 20 minutes between brushings. It is an add-on to whatever paste you use, Bioniq included, and it does not replace brushing.
What is verified, and what stays open
| What's checked | What the record shows | Verified or open |
|---|---|---|
| Maker | Dr. Kurt Wolff GmbH & Co. KG, Johanneswerkstr. 34-36, 33611 Bielefeld; commercial register HRA 11533, Amtsgericht Bielefeld; named as registrant in the WHOIS record for bioniq-repair.com | Verified, two independent records |
| Brand age | The Dr. Wolff Group's brand overview gives 2021 as the Bioniq brand's founding year; the bioniq-repair.com domain dates from 2019 | Verified as stated by the group and the registry |
| HAp concentration | 20%, stated on the US Classic and Plus pages and the German Repair-Zahncreme page | Verified: the brand publishes it |
| Particle form | "Micro-fine hydroxyapatite" (US page); "mikrokristalline Struktur" (German page) | Verified wording; no nm or µm figure anywhere we checked |
| Fluoride and SLS | "Fluoride & SLS Free" on the toothpaste pages; neither appears in the toothpaste ingredient lists | Verified for the toothpastes; the companion mouthwash lists SLS |
| Abrasivity (RDA) | "The RDA value falls within the normal/moderately abrasive range" | Open: no number published |
| Studies cited | 11 PubMed-indexed papers in our audit table; 9 disclose Dr. Wolff funding or employee authors; one further 2011 paper on nano-HAp cited on the research page | Verified via PubMed records, all linked below |
| US price | Classic 100 mL $16.99, two for $26.99 | Verified on the brand's US store |
| US shipping | US only; $5 under $50, free from $50; 3 to 4 business days | Verified on the brand's shipping page |
| Trustpilot | The page named Bioniq belongs to an unrelated supplement company | Verified: not a toothpaste rating |
| Regulatory record | No FDA warning letter, recall or lawsuit found in our searches | Web-search level check only |
Swipe sideways on mobile. All rows reflect the listed pages and records as checked on 25 September 2026.
How it comparesThe Bioniq range, side by side with a gum
Most searches for "bioniq toothpaste" are really about one tube, but the brand sells several. Here is what its own US and German pages say about each, with Minvelle added as the last column so you can see where a gum sits. The gum is not a toothpaste and is not meant to replace one; it is there because readers of this page often ask whether the two can be combined.
| Fact | Bioniq Classic (US) | Bioniq Plus Moist Gums (US) | Bioniq Repair-Zahncreme (DE) | Minvelle gum |
|---|---|---|---|---|
| Format | Toothpaste, 100 mL | Toothpaste, 100 mL | Toothpaste, 75 ml | Chewing gum, 1.9 g piece |
| Hydroxyapatite | 20%, "micro-fine" | 20% | 20%, "mikrokristallin" | 5.7 mg nano-HAp per piece (0.30% by weight) |
| Particle size published | No | No | No | Rods, 200 nm x 20 to 50 nm (supplier-stated) |
| Fluoride | None listed | None listed | None listed | None |
| Other named actives | Zinc PCA | Lactoferrin, sodium hyaluronate, zinc PCA, plant extracts | Zinc PCA | Xylitol, 817 mg per piece |
| Price on the brand store | $16.99; 2 for $26.99 | $18.99; 2 for $30.95 | 2 for €11.98, 3 for €17.97, 4 for €23.96 | €24.99 for 18 pieces |
| How you use it | Brushing | Brushing | Brushing | One piece a day, at least 20 minutes, between brushings |
Swipe sideways on mobile. Bioniq columns from bioniq-repair.com/en-us and /de-de, checked 25 September 2026. The White Filler variant ($19.95 single pack) is left out because its size was not confirmed.
Two things stand out. First, the core active and its 20% figure are the same across the range, so the choice between variants is mostly about the extras (lactoferrin and hyaluronate in Plus) and price. Second, none of the Bioniq variants publish a particle size, which is the one number this review keeps coming back to. For a wider view of pastes in this category, our ranking of fluoride-free toothpastes puts Bioniq next to seven others.
Part 1Which Bioniq? Two companies, one name
Before anything else, a disambiguation that changes how you should read the search results. If you type "bioniq toothpaste review" into Google, one of the top results at our check was a Trustpilot page at trustpilot.com/review/bioniq.com with a rating of 4.3 out of 5 across more than 850 reviews. That page is not about this toothpaste. It belongs to a different, unrelated company that sells personalized supplements and describes itself on that page as offering "the world's most personalized supplements, so you get precisely the nutrients YOU need, without guessing."
The toothpaste lives on different domains: bioniq-repair.com (German default, plus US and Malaysian English sections), bioniq-oralcare.com (UK and Singapore storefronts), bioniq-repair-zahnpflege.com, and a Singapore store at shop.dr-wolff.asia. All of them trace back to the same German manufacturer, covered in the next part. We found no Trustpilot page for any of those domains or for Dr. Wolff's oral-care brand.
So if you saw a Bioniq star rating and assumed it was about the toothpaste, it was not. The supplement company's reviews tell you about capsules and blood tests, not about how a hydroxyapatite paste feels or performs. The same care applies in reverse: nothing in this review is about the supplement business, and nothing said here should be read as a comment on it.
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Who makes it: Dr. Kurt Wolff, Bielefeld
Bioniq is made by Dr. Kurt Wolff GmbH & Co. KG, Johanneswerkstr. 34-36, 33611 Bielefeld, Germany. We confirmed that in two independent ways. The WHOIS record for bioniq-repair.com names "DR. KURT WOLFF GMBH & CO. KG" as the registrant organization, with a company webmaster email at drwolffgroup.com, and shows the domain was created in February 2019. The German commercial register lists the company at the same address under HRA 11533, Amtsgericht Bielefeld.
The company is not a startup. The Dr. Wolff Group's history page traces the business back to 1905, when, in its own words, "Pharmacist Dr. August Wolff founds 'Sudbracker Nährmittelwerke Vinces' in Bielefeld". That date belongs to the group, not to Bioniq: the group's brand overview gives 2021 as the founding year of the Bioniq brand itself, and the register history of the current legal entity starts in 2002. The group is family-run in its fourth generation, and its brand list includes Alpecin, Alcina, Plantur, Vagisan, Karex and Biorepair.
That last pair matters for toothpaste buyers. Karex and Biorepair are also hydroxyapatite oral-care brands (Biorepair itself belongs to the Italian Coswell S.p.A.; Dr. Wolff distributed it in Germany until launching Bioniq in 2021), and a 2020 paper cited by Bioniq describes its Dr. Wolff co-authors as employees of a company "which markets oral care products (Biorepair and Karex)" (Steinert 2020, PMID 32354134). If you have used Karex, you have used a product from the same manufacturer. The Bioniq pages we read do not explain how the three formulas relate to each other, so we do not speculate about whether they are the same paste in different packaging.
We found no dentist-founder story anywhere on the brand's pages, and the brand does not claim one. August Wolff is described as a pharmacist. No single person is credited as the founder of Bioniq. For US buyers, the brand's US FAQ gives a returns address for "Dr. Wolff USA Distribution Inc", 300 Cedar Lane Suite A, Edison, NJ 08817, which tells you there is a US distribution entity behind the US store.
Part 3The product line, variant by variant
The brand's US store lists three toothpastes: Bioniq Classic Hydroxyapatite Toothpaste, Bioniq Hydroxyapatite Toothpaste Plus Moist Gums, and Bioniq White Filler Hydroxyapatite Toothpaste. The German store has matching products under German names: Bioniq Repair-Zahncreme (the core paste), Bioniq Repair-Zahncreme Zahnfleisch-Schutz with hyaluronic acid and lactoferrin, and Bioniq White Filler Zahnpasta.
The German store also carries a variant called Bioniq Repair-Zahncreme Sensitiv Akut, which we did not find as a separate product on the US store at our check. And it sells a companion product, Bioniq Repair Zahn-Milch, a 400 ml mouthwash the brand positions next to the toothpaste; it comes up again in Part 6 because of one ingredient.
We searched every brand page we fetched for a kids' product and found no mention of one. That does not prove no kids' paste exists somewhere; it means we did not find one on the pages we checked, so this review makes no claims about children's use.
In short: when people search "bioniq repair toothpaste", they mean the Classic paste in the US or the Repair-Zahncreme in Germany. The rest of this review focuses on that core formula, and notes where the other variants differ.
Part 4The ingredient list, line by line
Here is the US Classic ingredient list, exactly as the brand publishes it, including a spelling slip in one ingredient name: Water, Hydroxyapatite, Hydrated Silica, Glycerin, Sorbitol, Flavor, Sodium Myristoyl Sarcosinate, Cellulose Gum, Silica, Tetrapotassium Pyrophosphate, Zinc PCA, Sodium Methyl Coyly Taurate, Sodium Saccharin, Citric Acid, Phenoxyethanol, Propylparaben, Methylparaben, Sodium Benzoate, Benzyl Alcohol, Limonene. "Coyly" is the brand's own spelling; the standard name is Sodium Methyl Cocoyl Taurate, which is how the German list spells it.
What each group does, in plain terms:
- Water and hydroxyapatite. Hydroxyapatite in second place, right after water, is consistent with the 20% claim. Ingredient lists run in descending order of amount for ingredients at 1% or more, so the active sitting this high is what you would expect from a paste that is one fifth hydroxyapatite.
- Hydrated silica and silica. The cleaning abrasives. The brand's FAQ says "Only abrasive media of mineral origin (silica and hydrated silica) are used." More on abrasivity in Part 7.
- Glycerin, sorbitol and cellulose gum. The body of the paste: they keep it moist and give it its texture. Sorbitol also adds some sweetness.
- Flavor, sodium saccharin, limonene, benzyl alcohol. Taste. Limonene and benzyl alcohol are aroma components that are declared by name.
- Sodium myristoyl sarcosinate and sodium methyl cocoyl taurate. The foaming and cleaning agents, used here in place of sodium lauryl sulfate.
- Tetrapotassium pyrophosphate. A phosphate salt commonly used in toothpastes to help with tartar.
- Zinc PCA. A zinc compound. It appears in every Bioniq toothpaste list we checked.
- Citric acid. Adjusts the pH of the paste.
- Phenoxyethanol, propylparaben, methylparaben, sodium benzoate. Preservatives. Two parabens are listed. If you avoid parabens, note that the US Plus Moist Gums list we checked does not include them and uses potassium sorbate instead.
The US and German lists are not identical
The German Repair-Zahncreme list, for what the brand presents as the same 20% formula, reads: Aqua, Hydroxyapatite, Glycerin, Hydrated Silica, Sorbitol, Aroma, Sodium Myristoyl Sarcosinate, Cellulose Gum, Silica, Tetrapotassium Pyrophosphate, Zinc PCA, Sodium Methyl Cocoyl Taurate, Sodium Saccharin, Citric Acid, Phenoxyethanol, Propylparaben, Methylparaben, Sodium Benzoate, Menthol, Anethole, Benzyl Alcohol, Beta-Caryophyllene, Terpineol, Limonene, Pinene.
Compared with the US list, five flavor components appear only in the German version: menthol, anethole, beta-caryophyllene, terpineol and pinene. The order of glycerin and hydrated silica is also swapped. This could be a regional flavor difference, which is common, or a less complete US listing. The brand's pages do not say which, and we do not assume. If you react to any of those five, check the tube you actually hold rather than either web page.
The Plus Moist Gums list
The Plus variant keeps the water, hydroxyapatite, glycerin and silica base and adds lactoferrin, sodium hyaluronate, witch hazel leaf extract, spirulina extract, calendula flower extract, tocopheryl acetate, cocamidopropyl betaine and sodium chloride. Its preservative system is phenoxyethanol, sodium benzoate and potassium sorbate. For readers who asked: we found no xylitol and no potassium nitrate in any Bioniq toothpaste list we checked.
Part 520% hydroxyapatite, micro, not nano
This is the most useful thing about Bioniq for a careful buyer, and the part most reviews skip. The brand publishes a concentration. The US Classic page title reads "Bioniq Classic Hydroxyapatite Toothpaste: with 20% artificial enamel", the product data on the same page says "Toothpaste with 20% Hydroxyapatite", the Plus page says "With 20% Hydroxyapatite", and the German page says "20% Hydroxylapatit". Across every market we checked, the number is the same.
That puts Bioniq among a small group of hydroxyapatite pastes that print a percentage at all. Many brands in this category name the ingredient and stop there. With a percentage, you know what you are paying for, and you can compare it with the concentrations used in the studies. Our comparison of 11 hydroxyapatite toothpastes shows which other brands print one.
What "micro" means here
The brand is also direct about particle form, and it chooses the word micro. The US page says, verbatim: "Micro-fine hydroxyapatite supports tooth and oral health with every brushing." The German page opens with "Mikrofeiner Wirkstoff repariert Defekte" (micro-fine active ingredient repairs defects) and describes "die mikrokristalline Struktur des Hydroxylapatits", the microcrystalline structure of the hydroxyapatite. Those are the brand's words, and they are consistent across languages.
What the brand does not give is a number. We searched every brand page we fetched, in German and English, for particle sizes in nanometers or micrometers and found none. So "micro" is a description, not a specification. If particle size matters to you, you would have to ask the company. Our explainer on nano versus non-nano hydroxyapatite covers why size gets discussed so much in this category.
A plastics answer that is easy to misread
One FAQ answer on the US Classic page can look like a particle-size statement but is not. Asked about plastic microparticles, the brand writes: "Since all Bioniq® products are based on the principle of biomimetics, we never use ingredients of concern. Therefore, the Classic Hydroxyapatite Toothpaste contains no micro- or nanoplastics. We do not use polyethylene plastic beads, so-called microbeads, as abrasive agents in our toothpastes." That is about plastic beads, not about the size of the hydroxyapatite. We mention it only so no one quotes it as a nano or micro claim for the active.
Wellnesse also uses micro-sized hydroxyapatite and makes some of the boldest claims in the category, which our Wellnesse toothpaste review checks one by one against the trials.
A nano paper on a micro product's research page
Here are two facts, side by side, and we leave the weighing to you. The brand's English page "Research at Dr. Wolff" states that "we were able to demonstrate, in collaboration with Charité Berlin, that HAP remineralizes dentin and enamel more effectively than fluoride", and cites a 2011 study in support. That study is Tschoppe and colleagues, "Enamel and dentine remineralization by nano-hydroxyapatite toothpastes", Journal of Dentistry, 2011 (PMID 21504777). It is an in vitro study, the test products are coded by letters rather than named, and the abstract describes the pastes tested as nano-hydroxyapatite. Its PubMed record lists Charité Berlin affiliations, names no Dr. Wolff co-author and carries no conflict-of-interest statement.
The second fact: the brand's current product pages describe the Bioniq active as "micro-fine" and "microcrystalline". The research page does not explain how a nano-hydroxyapatite study relates to a paste marketed as micro. Whether any product in that 2011 paper was an earlier version of a Dr. Wolff paste is not stated in the abstract, and we did not see the full text, so this review does not claim either way.
Bioniq and Minvelle, side by side
| Fact | Bioniq Classic (brand US page, 25 Sep 2026) | Minvelle |
|---|---|---|
| Hydroxyapatite per tube or piece | 20% of the paste, described as "micro-fine" | 5.7 mg nano-hydroxyapatite per 1.9 g piece, printed on the box |
| Fluoride and other actives | Fluoride-free; zinc PCA | Fluoride-free; 817 mg xylitol per piece |
| What is published | Concentration and full ingredient list; no particle size, no RDA number | Dose, particle size (supplier-stated) and batch certificate |
| Price, pack and directions | $16.99 per 100 mL tube; brush as a toothpaste | €24.99 for 18 pieces; 1 piece a day, at least 20 minutes |
Minvelle is for people who want a measured dose of hydroxyapatite between brushings; if you want a fluoride-free toothpaste with a published concentration for your daily brushing, Bioniq is the better buy.
Minvelle prints the dose on the box: 5.7 mg nano-hydroxyapatite per piece. See the gum.
Part 6Fluoride-free and SLS-free: where the claim applies
Both the Classic and the Plus product pages carry the same line, verbatim: "Fluoride & SLS Free: Bioniq gently cleans teeth without fluoride or Sodium Lauryl Sulfate" (the Plus page reads "Bioniq PLUS" in place of "Bioniq"). The ingredient lists back that up. No fluoride compound appears in any Bioniq toothpaste list we checked, and neither does sodium lauryl sulfate; the foaming work is done by sodium myristoyl sarcosinate and sodium methyl cocoyl taurate instead.
One product in the wider family is different. Bioniq Repair Zahn-Milch, the 400 ml companion mouthwash sold on the German store at €6.99, lists this ingredient set: Aqua, Sorbitol, Xylitol, Hydroxyapatite, Cellulose Gum, Zinc PCA, PEG-40 Hydrogenated Castor Oil, Sodium Lauryl Sulfate, Sodium Methyl Cocoyl Taurate, Sodium Saccharin, Sodium Myristoyl Sarcosinate, Lactoferrin, Sodium Hyaluronate, Phenoxyethanol, Sodium Benzoate, Aroma, Menthol, Anethole, Beta-Caryophyllene, Terpineol, Limonene, Pinene.
So the facts are: the toothpastes are marketed as "Fluoride & SLS Free", and the companion Zahn-Milch in the same Repair range lists sodium lauryl sulfate. Both statements come from the brand's own pages. If SLS is the reason you are choosing Bioniq, the toothpaste fits that reason and the Zahn-Milch, as listed, does not.
Whether fluoride-free is right for you is a separate question, and one for your dentist. Our guide on nano-hydroxyapatite versus fluoride lays out what each does, and the Paszynska trial in Part 8 is the most direct comparison the brand cites.
Part 7How abrasive is it? No number, one sentence
Abrasivity is measured as RDA, relative dentin abrasivity, and many brands publish it. Bioniq does not. The FAQ on the US Classic page says: "The RDA value falls within the normal/moderately abrasive range. All of our toothpastes are suitable for daily use, even for sensitive teeth." That is the brand's statement, and it is qualitative. We found no RDA number on any brand page we checked.
Without a number you cannot compare Bioniq's abrasivity with another paste directly. The abrasives listed are hydrated silica and silica, both standard in toothpaste. If abrasivity matters to you, for example because of exposed root surfaces, ask the company for the figure or ask your dentist. Our explainer on toothpaste abrasivity and the RDA number shows what the ranges mean.
Part 8The studies, paper by paper
Bioniq cites research on two pages: a German studies page and an English page called "Research at Dr. Wolff". We took every citation from both that resolves to a PubMed record and fetched the record directly from the National Library of Medicine on 25 September 2026. For each paper we noted what it tested, the design, the number of participants where there were any, the main result as the abstract states it, and whether the record discloses Dr. Wolff funding or Dr. Wolff employees among the authors.
A note on how to read the last column. Industry-funded research is normal in oral care, and a disclosure is a sign the authors followed the rules. The column is there so you know who stood behind each paper, not to rank the papers. The design column matters more for what a paper can show: a lab study with acid in a beaker answers a different question from an 18-month trial in people.
| Paper | What it tested and how | Result, per the abstract | Dr. Wolff disclosure in the PubMed record |
|---|---|---|---|
| Paszynska 2023, Frontiers in Public Health | Hydroxyapatite toothpaste vs 1450 ppm sodium fluoride toothpaste; 18-month double-blind randomized trial, non-inferiority design; 189 adults (ITT), 171 per protocol; NCT04756557 | No increase in DMFS in 89.3% (HAp) vs 87.4% (fluoride) per protocol; HAp "not statistically inferior" | Yes: three of eight authors are Dr. Wolff employees |
| Pawinska 2024, Journal of Dentistry | Updated systematic review and meta-analysis; 18 studies retrieved, 5 clinical and 8 in situ trials in the meta-analysis | Concludes HAp-containing products reduce caries risk across the pooled evidence | Yes: two authors employed by Dr. Wolff; all authors received Dr. Wolff travel grants |
| Cieplik 2020, BMC Oral Health | In vitro: S. mutans cultures and biofilms vs silica and no-HAp controls | HAp released calcium and buffered bacterial acid under the tested conditions | Yes: funded in part by a Dr. Wolff grant; two authors are employees |
| Fandrich 2026, BDJ Open | In vitro: particulate HAp added to four acids, Sprite and Coca-Cola | Neutralized 98.0 to 99.9% of acidic protons at equilibrium | Yes: some authors are Dr. Wolff employees |
| Limeback 2023, Dentistry Journal | Systematic review of whitening; 17 of 279 studies included, in vitro and in vivo | Concludes regular HAp use "effectively whitens teeth"; in vivo evidence rated "modest", from 6 preliminary clinical trials | Yes: two authors are Dr. Wolff employees |
| Enax 2025, Dentistry Journal | In vitro staining and brushing vs a blue-covarine whitening paste | More stain removal after 30 s of brushing; comparable after 180 s | Yes: three authors are Dr. Wolff employees; a fourth has received Dr. Wolff funding |
| Harks 2016, PLOS ONE | mHA dentifrice vs AmF/SnF2 fluoride dentifrice; 12-week randomized double-blind two-center trial; 70 periodontitis patients (33 vs 34 analyzed) | Primary outcome, plaque formation rate, did not differ significantly; secondary measures improved in both groups without significant between-group differences | Yes: all study affairs funded exclusively by Dr. Wolff |
| Limeback 2023, Biomimetics | Updated systematic review and meta-analysis of hypersensitivity; 44 human trials | Reports HAp reduced dentin hypersensitivity 39.5% vs placebo and 23% vs fluoride; no significant difference vs other desensitizers | Yes: two authors are Dr. Wolff employees |
| Steinert 2020, Biomimetics | 4-week observational questionnaire study, no control arm; 46 participants analyzed from 3 German practices | Self-reported improvements after 4 weeks | Yes: two authors are Dr. Wolff employees |
| Amaechi 2019, BDJ Open | 10% HAp paste vs 500 ppm amine fluoride paste; in situ double-blind randomized crossover; 30 adults, 14 days per arm; NCT03681340 | Remineralization and lesion-depth reduction not statistically different between the two pastes | No: "The authors declare no competing interests" |
| Kensche 2017, Archives of Oral Biology | In situ single mouthrinse, 5% HAp microclusters vs 0.2% chlorhexidine and no rinse; 9 participants | HAp rinse reduced initial bacterial adhesion vs control (p<0.001), less than chlorhexidine | None found in the PubMed record (full text not checked) |
Swipe sideways on mobile. Each paper links to its PubMed record. Disclosures quoted or summarized from the PubMed record only.
Counting the last column: 9 of the 11 papers in the table disclose Dr. Kurt Wolff GmbH & Co. KG funding or Dr. Wolff employees among the authors. Two do not: Amaechi 2019 states no competing interests, and the PubMed record for Kensche 2017 contains no disclosure either way. The 2011 Tschoppe paper discussed in Part 5 is the twelfth PubMed-indexed citation; its record names no Dr. Wolff author and carries no disclosure statement.
The strongest paper: the 18-month trial
If you read only one of these, read Paszynska 2023 (PMID 37533523). It compared a fluoride-free hydroxyapatite toothpaste with a toothpaste containing 1450 ppm fluoride, over 18 months, double-blind, in adults. It was designed as a non-inferiority trial, which asks a specific question: is the new paste not meaningfully worse than the standard one, within a margin set in advance? By the per-protocol analysis, 89.3% of the hydroxyapatite group and 87.4% of the fluoride group showed no increase in their DMFS score, a count of decayed, missing and filled tooth surfaces. The authors report the hydroxyapatite paste was not statistically inferior. The trial is registered as NCT04756557, and three of its eight authors are Dr. Wolff employees.
Two cautions in reading it. "Not inferior" is not the same as "better": the trial was not built to show the hydroxyapatite paste beats fluoride. And it tested one specific hydroxyapatite toothpaste; the abstract does not use the Bioniq name, so we report it as the brand's cited evidence rather than as a trial of the exact tube on sale today.
The trial whose main result was not significant
Harks 2016 (PMID 27467683) is worth reading closely because the brand cites it and because its main result was neutral. It was a 12-week, randomized, double-blind trial at two centers in 70 people with periodontitis, comparing a microcrystalline hydroxyapatite paste (mHA) with a fluoride paste containing amine fluoride and stannous fluoride. The primary outcome was plaque formation rate. In the mHA group it went from 51.7% to 48.4%; in the fluoride group from 52.3% to 46.1%. Neither change was statistically significant, and the paper reports no significant difference between the groups. Secondary measures improved in both groups, again without significant differences between them. The study was funded exclusively by Dr. Wolff.
That is an honest, published result, and credit goes to the authors and the funder for publishing it. For a buyer it means this particular trial supports "comparable to the fluoride paste tested" on these gum measures, not "better".
The independent-looking one
Amaechi 2019 (PMID 31839988) is the only paper in the table whose record states no competing interests. Thirty adults wore enamel samples in their mouths for 14 days per arm, using either a 10% hydroxyapatite paste or a 500 ppm amine fluoride paste, in a double-blind crossover. Remineralization and lesion-depth reduction were not statistically different between the two. Note the concentration: the paper tested 10% hydroxyapatite, not 20%.
Lab studies and reviews
Four papers are laboratory work (Cieplik 2020, Fandrich 2026, Enax 2025) or single-use in situ tests (Kensche 2017). They show what hydroxyapatite does to bacteria, acid or stains under controlled conditions. They are useful for understanding the mechanism and do not, on their own, tell you what happens in months of daily brushing. Fandrich 2026 was published in BDJ Open in March 2026, per its PubMed record.
Three are reviews: Pawinska 2024 on caries, and two by Limeback 2023, one on whitening and one on dentin hypersensitivity. The whitening review itself rates the in vivo evidence as "modest", based on six preliminary clinical trials. The hypersensitivity review reports the reductions shown in the table; we report that finding as the authors state it and make no claim of our own about it. Our wider summary of hydroxyapatite toothpaste studies puts these papers next to research from other groups.
Citations we could not check
Both brand pages also cite a paper by Fabritius-Vilpoux, Enax and Herbig on affinity parameters of synthetic hydroxyapatite, in a journal called Bioinspired, Biomimetic and Nanobiomaterials, presented as a Max Planck Institute collaboration. We searched PubMed by title and by author combinations and found no record. The journal does not appear to be indexed there. That does not mean the paper does not exist; it means we could not verify it the same way, so it is not counted in any number above.
If you want to see how this research base is discussed more broadly, including why some dentists are cautious about hydroxyapatite, our piece on why many dentists do not recommend hydroxyapatite yet covers the reasons in plain terms.
Part 9Price per tube, price per month
All prices below are from the brand's own stores on 25 September 2026. Marketplace prices change daily and we did not verify them, so they are not quoted.
| Product and store | Pack | Price | Per 100 mL |
|---|---|---|---|
| Classic, US store | 100 mL single | $16.99 | $16.99 |
| Classic, US store | 2 x 100 mL | $26.99 (shown against $33.98) | $13.49 |
| Plus Moist Gums, US store | 100 mL single | $18.99 | $18.99 |
| Plus Moist Gums, US store | 2 x 100 mL | $30.95 | $15.48 |
| White Filler, US store | Single pack | $19.95 | Size not confirmed |
| Repair-Zahncreme, German store | 2 x 75 ml | €11.98 | €7.99 |
| Repair-Zahncreme, German store | 3 x 75 ml | €17.97 | €7.99 |
| Repair-Zahncreme, German store | 4 x 75 ml | €23.96 | €7.99 |
| Repair Zahn-Milch, German store | 400 ml | €6.99 (list price) | Not a toothpaste |
Per-100 mL figures are our arithmetic from the listed prices, rounded to the cent.
Two observations. In the US, the two-pack is the value option: $13.49 per tube instead of $16.99. In Germany, the per-tube price is €5.99 whether you buy two, three or four tubes, so the larger pack does not lower the unit price; it only saves reorders.
How long a tube lasts depends on how much you put on the brush and how often you brush. The brand's pages we checked do not state a recommended amount per brushing, so we do not invent a monthly figure. If you already know how long a standard 100 mL tube lasts you, that same span is a reasonable starting point for Bioniq Classic.
For comparison, and only because readers ask: a box of Minvelle costs €24.99 for 18 pieces, and at one piece a day one box covers 18 days. That is a different product doing a different job, so it is an add-on cost next to your toothpaste, not an alternative to it.
US shipping from the brand store is a flat $5 below $50 and free from $50, which means two two-packs of Classic ($53.98) clear the free-shipping line.
Part 10Where to buy it: US, UK and Europe
United States. The brand runs its own US store at bioniq-repair.com/en-us, with prices in dollars and a US returns address. Its shipping page says, verbatim: "Currently, we only offer shipping within the United States." Delivery is quoted at 3 to 4 business days, with no express option. The product is also listed on Amazon.com.
United Kingdom. The brand has a separate UK storefront at bioniq-oralcare.com/en-gb, with its own product pages and FAQ. The product is also listed at Boots, the UK high-street retailer, and on Amazon.co.uk. We did not confirm whether the UK storefront ships outside the UK.
Germany and Austria. The home market store is bioniq-repair.com/de-de. The paste is also sold at dm, the drugstore chain, under its own Bioniq brand page, and on Amazon.de.
Asia. There is a Malaysian English section at bioniq-repair.com/en-my, a Singapore storefront at bioniq-oralcare.com/en-sg, and a Singapore store at shop.dr-wolff.asia. We found these through search and did not check them beyond their page titles.
Buying from the brand's own store has one advantage worth naming: you get the ingredient list and the returns address for the exact market you are buying in. As Part 4 showed, those lists can differ by country.
Part 11Returns and support
For US orders, the brand's FAQ gives the returns address as Dr. Wolff USA Distribution Inc, 300 Cedar Lane Suite A, Edison, NJ 08817. We did not find a money-back guarantee headline on the product pages we read, and we are not quoting return windows we did not verify. If returns matter to you, read the current returns section on the brand's FAQ before ordering, and keep your order confirmation.
For readers in the EU and UK: statutory consumer rights on distance purchases apply regardless of a store's own policy wording.
Part 12Reviews and the complaint record
Three sources of opinion exist for this toothpaste, and each has limits.
The brand's own site. The German product page shows small Judge.me review widgets on different product tiles: 4.81 stars from 16 reviews, 5.00 stars from 2, and one tile with no reviews. The US Classic page showed no reviews in the same widget at our check. Sixteen reviews on the seller's own site is a thin sample, and we do not treat it as representative.
Marketplaces. Most of the third-party review volume sits on Amazon listings in Germany, the US and the UK. We did not verify current star ratings or counts on those listings on the day of writing, so we do not quote any. If you want a number, open the listing for your country and read the lowest-rated reviews first; they tell you more about fit than the five-star ones.
Trustpilot. As covered in Part 1, the Trustpilot page named Bioniq is about an unrelated supplements company. It says nothing about the toothpaste.
On the regulatory side, we searched the FDA's warning-letter listings and the general web for Dr. Kurt Wolff and Bioniq on 25 September 2026 and found no warning letters, no recall notices for Bioniq oral-care products, and no lawsuits or class actions. That was a web-search level check, not a search of court databases, so treat it as "none found" rather than "none exist".
What we did not find is a body of verified complaint themes. The YouTube and blog content that ranks for "is bioniq toothpaste legit" is mostly first impressions, and we do not summarize it as evidence.
Part 13Who it suits, and who should skip it
Bioniq is a reasonable fit if
- You want a fluoride-free toothpaste and prefer one that publishes its hydroxyapatite concentration.
- You want to avoid sodium lauryl sulfate in your toothpaste.
- You prefer a product from an established manufacturer with a registered address and a long company history.
- You are in the US and want to buy direct from the brand, or in the UK and want a high-street option at Boots.
- You are fine with a paste described as micro-scale and do not need a nano product.
You may want to skip it if
- You avoid parabens: the Classic lists propylparaben and methylparaben. The Plus variant we checked does not.
- You want a published RDA number before choosing a paste.
- You want a published particle size for the active.
- Your dentist has advised fluoride for your situation. Fluoride-free is a choice to make with your dentist, not around them.
- You need a kids' toothpaste: we found no kids' product on the brand pages we checked.
Where a gum fits, and where it does not
This is a Minvelle blog, so here is the honest version of how our product relates to this one. A toothpaste and a gum do different jobs. You brush twice a day for two minutes; a toothpaste like Bioniq is built for that. A gum is chewed between brushings, when a toothbrush is not in reach.
Minvelle is a nano-hydroxyapatite chewing gum: 5.7 mg per 1.9 g piece (0.30% by weight), printed on the box, sweetened with xylitol at 817 mg per piece, fluoride-free, 14 ingredients. It contains egg, so it is not vegan. You chew one piece a day for at least 20 minutes, and a box holds 18 pieces for €24.99. The particle is rod-shaped, 200 nm by 20 to 50 nm, as stated by our supplier, and we publish a lab-tested batch certificate.
It does not replace brushing, and it does not replace your toothpaste, Bioniq or otherwise. There is no clinical trial on the gum, and we do not claim one. What it offers is a measured amount of hydroxyapatite and xylitol in the hours between brushings, for people who like the idea of a remineralizing routine that goes beyond the brush. If you are happy with your toothpaste and do not want another step, you do not need it.
Part 15Fairness: what Bioniq does well
A review that only lists gaps is not a fair review, so here is what Bioniq does well, stated plainly.
- It publishes a concentration. 20% hydroxyapatite, stated on the page, consistent across markets, and consistent with the ingredient order. Many brands in this category do not do this.
- It says micro when it means micro. The brand does not dress its active up as nano on the product pages; it uses "micro-fine" and "microcrystalline" in both languages.
- Full ingredient lists are public on the product pages, in both the US and German stores.
- The maker is identifiable. A registered German company with a public address, a commercial register entry and a US distribution entity with a returns address.
- Its research is disclosed. The papers it cites carry their funding and employment disclosures, and it cites a published trial whose primary outcome was not significant rather than only positive results.
- Its best trial is a real trial. Eighteen months, double-blind, 189 adults, registered as NCT04756557, against a 1450 ppm fluoride paste.
- US buyers can buy direct, with clear shipping terms and a US address.
The open items are few and specific: a particle size, an RDA number, an explanation of the 2011 nano paper on the research page, the flavor differences between the US and German lists, and the SLS in the companion Zahn-Milch. Any of those could be closed with a line on a page.
Part 16How we checked, and our conflict
Everything in this review comes from primary sources checked on 25 September 2026: the brand's US and German product pages, its US FAQ, shipping page and research page, the German studies page, the Dr. Wolff Group history and brand-overview pages, the WHOIS record for bioniq-repair.com, the commercial register entry for HRA 11533, and the PubMed record of every cited study, fetched directly from the National Library of Medicine. We did not buy or test the toothpaste, and we make no claims about taste or feel.
Our conflict of interest: Minvelle sells a hydroxyapatite gum. We do not sell a toothpaste and we do not compete with Bioniq for the same use, but we benefit when people care about hydroxyapatite and about published numbers. That is why this review sticks to the brand's own words and to records you can re-check, and gives the brand full credit where it earns it.
Facts checked on 25 September 2026 from the sources below; if Bioniq changes its pages, tell us and we will update.
Hydroxyapatite (HAp): The calcium-phosphate mineral that tooth enamel is mostly made of. In oral care it is made synthetically and added to toothpastes and gums in different particle sizes and amounts.
Micro vs nano: Particle scale. Nano particles are measured in nanometers (billionths of a meter), micro particles in micrometers (millionths). Bioniq calls its active "micro-fine" without giving a number.
INCI: The standard naming system for cosmetic ingredient lists. Ingredients at 1% or more are listed in descending order of amount.
RDA: Relative dentin abrasivity, a lab measure of how abrasive a toothpaste is. Bioniq describes its RDA as "normal/moderately abrasive" but publishes no number.
SLS: Sodium lauryl sulfate, a common foaming agent. The Bioniq toothpastes do not list it; the companion Zahn-Milch does.
Non-inferiority trial: A trial designed to show a new treatment is not worse than a standard one by more than a preset margin. It does not test whether the new one is better.
DMFS: A count of decayed, missing and filled tooth surfaces, used to track new decay in trials.
In vitro, in situ: In vitro means in the lab, outside the body. In situ means samples worn in the mouth, often on a removable appliance.
PMID: PubMed's index number for a paper. Every study claim in this review links to one.
The things people actually ask
Is Bioniq toothpaste legit?
Yes, in the plain sense: it is a real toothpaste from a real, registered manufacturer. Bioniq is made by Dr. Kurt Wolff GmbH & Co. KG of Bielefeld, Germany, entered in the commercial register at Amtsgericht Bielefeld under HRA 11533, the same company behind Alpecin, Plantur and Karex, and the German distributor of the Italian Biorepair toothpaste until 2021. The brand publishes its full ingredient list and a 20% hydroxyapatite figure, and it sells directly in the US through its own store. What it does not publish is a particle size in nanometers or micrometers, and most of the research it cites discloses Dr. Wolff funding or employee authors.
Who makes Bioniq toothpaste?
Dr. Kurt Wolff GmbH & Co. KG, Johanneswerkstr. 34-36, 33611 Bielefeld, Germany. The WHOIS record for bioniq-repair.com names that company as the registrant, and the German commercial register lists it under HRA 11533 at Amtsgericht Bielefeld. The Dr. Wolff Group's own brand overview gives 2021 as the founding year of the Bioniq brand. US returns go to Dr. Wolff USA Distribution Inc in Edison, New Jersey, per the brand's US FAQ.
How much hydroxyapatite is in Bioniq Repair toothpaste?
20%, per the brand's own pages. The US Classic page title reads "with 20% artificial enamel", its product data says "Toothpaste with 20% Hydroxyapatite", the Plus Moist Gums page repeats "With 20% Hydroxyapatite", and the German page says "20% Hydroxylapatit". Hydroxyapatite is listed second on the ingredient list, right after water, which fits a high concentration.
Is the hydroxyapatite in Bioniq nano or micro?
The brand describes it as micro. The US product page says "Micro-fine hydroxyapatite" and the German page describes a "mikrokristalline Struktur", a microcrystalline structure. No numeric particle size is given on any brand page we checked. One detail to know: the brand's English research page cites a 2011 study titled "Enamel and dentine remineralization by nano-hydroxyapatite toothpastes" in support of its claims, and that paper describes nano-hydroxyapatite.
Is Bioniq toothpaste fluoride-free and SLS-free?
The Classic and Plus product pages say "Fluoride & SLS Free", and neither toothpaste ingredient list we checked contains fluoride or sodium lauryl sulfate. The companion mouthwash in the same Repair family, Bioniq Repair Zahn-Milch, lists sodium lauryl sulfate in its ingredients. So the SLS-free claim applies to the toothpastes, not to every product sold under the name.
What does the research behind Bioniq actually show?
The strongest paper the brand cites is an 18-month, double-blind trial in 189 adults (Paszynska 2023, PMID 37533523), which found the hydroxyapatite toothpaste not statistically inferior to a 1450 ppm fluoride toothpaste on new decay. A 2016 trial in periodontitis patients (Harks, PMID 27467683) found no significant difference in its primary outcome, plaque formation rate, between the hydroxyapatite paste and a fluoride paste. Nine of the 11 cited papers in our audit table disclose Dr. Wolff funding or employee authors.
How much does Bioniq toothpaste cost?
On the brand's US store on 25 September 2026: Classic 100 mL $16.99 or $26.99 for two, Plus Moist Gums $18.99 or $30.95 for two, White Filler $19.95. On the German store the 75 ml Repair-Zahncreme comes in 2, 3 and 4 packs at €11.98, €17.97 and €23.96, which is €5.99 per tube in every pack size. US shipping is $5 under $50 and free from $50.
Where can I buy Bioniq toothpaste in the US and UK?
In the US, the brand runs its own store at bioniq-repair.com/en-us, which ships only within the United States, and the product is also listed on Amazon.com. In the UK, there is a separate brand storefront at bioniq-oralcare.com/en-gb, and the product is listed at Boots and on Amazon.co.uk. In Germany and Austria it is sold through the brand's German store, dm and Amazon.de.
Is the Bioniq Trustpilot rating about the toothpaste?
No. The Trustpilot page named Bioniq, at trustpilot.com/review/bioniq.com, belongs to an unrelated personalized-supplements company that describes itself as offering "the world's most personalized supplements". Its rating says nothing about the toothpaste. We found no Trustpilot page for bioniq-repair.com or for Dr. Wolff's oral-care brand.
What is the difference between Bioniq, Biorepair and Karex?
Karex and Bioniq are brands of Dr. Kurt Wolff GmbH & Co. KG. Biorepair is a trademark of the Italian company Coswell S.p.A.: Dr. Wolff sold a Biorepair toothpaste in Germany until 2021, when it launched Bioniq as its own brand, and Coswell still sells Biorepair in Europe (listed at dm.at and Müller on 25 September 2026). A 2020 paper's disclosure from that period describes Dr. Wolff as a company "which markets oral care products (Biorepair and Karex)". The Bioniq pages we checked do not explain how the three formulas relate, so we do not guess.
Can I use a hydroxyapatite gum alongside Bioniq?
Yes, they do different jobs. A toothpaste works while you brush; a gum is chewed between brushings. Minvelle is a nano-hydroxyapatite chewing gum with 5.7 mg per 1.9 g piece, one piece a day, chewed for at least 20 minutes. It is an add-on between brushings and does not replace brushing or your toothpaste.
Medical disclaimer: this article is educational and is no medical advice. It does not diagnose, treat or replace professional care. Talk to your dentist before changing your oral-care routine, including before switching to a fluoride-free toothpaste. Product formulations, listings and ingredient lists change over time; always check the current label and consult your dentist about your individual enamel and gum health.
- Bioniq US store, bioniq-repair.com/en-us: Classic and Plus Moist Gums product pages (20% claim, "micro-fine" wording, ingredient lists, "Fluoride & SLS Free", RDA and plastics FAQ answers, prices), FAQ (returns address), shipping page, and "Research at Dr. Wolff" page, checked 25 September 2026
- Bioniq German store, bioniq-repair.com/de-de: Repair-Zahncreme page (20% Hydroxylapatit, "mikrokristalline Struktur", ingredient list, pack prices), Repair Zahn-Milch ingredient list, and studies page, checked 25 September 2026
- Dr. Wolff Group history page: 1905 founding quote
- Dr. Wolff Group brand overview, Bioniq: 2021 brand founding year
- WHOIS record for bioniq-repair.com: registrant Dr. Kurt Wolff GmbH & Co. KG, created February 2019, checked 25 September 2026
- Commercial register, Amtsgericht Bielefeld, HRA 11533: Dr. Kurt Wolff GmbH & Co. KG, Johanneswerkstr. 34-36, 33611 Bielefeld (via North Data company record)
- Trustpilot, bioniq.com: the unrelated personalized-supplements company, quoted in Part 1
- PubMed, PMID 37533523: Paszynska et al., 18-month HAp vs fluoride toothpaste trial, Frontiers in Public Health 2023
- PubMed, PMID 39471896: Pawinska et al., systematic review and meta-analysis, Journal of Dentistry 2024
- PubMed, PMID 32199447: Cieplik et al., in vitro S. mutans study, BMC Oral Health 2020
- PubMed, PMID 41881909: Fandrich et al., in vitro acid neutralization, BDJ Open 2026
- PubMed, PMID 36826195: Limeback et al., systematic review of whitening, Dentistry Journal 2023
- PubMed, PMID 40277473: Enax et al., in vitro stain removal, Dentistry Journal 2025
- PubMed, PMID 27467683: Harks et al., 12-week trial in periodontitis patients, PLOS ONE 2016
- PubMed, PMID 36648809: Limeback et al., systematic review of dentin hypersensitivity, Biomimetics 2023
- PubMed, PMID 32354134: Steinert et al., 4-week observational study, Biomimetics 2020
- PubMed, PMID 31839988: Amaechi et al., in situ crossover vs 500 ppm fluoride, BDJ Open 2019
- PubMed, PMID 28364672: Kensche et al., in situ mouthrinse study, Archives of Oral Biology 2017
- PubMed, PMID 21504777: Tschoppe et al., in vitro nano-hydroxyapatite toothpastes, Journal of Dentistry 2011
About the author
Max, Founder of Minvelle, builds an oral-care brand around one rule: publish the numbers, cite the sources, and say plainly what a product cannot do. He is not a dentist and does not play one online, which is why every article on this blog ends by pointing you to yours. The full formula behind Minvelle, every ingredient and dose, is public on the transparency page.
The bottom line. Bioniq Repair is a fluoride-free, SLS-free toothpaste from a long-established German manufacturer, with a published 20% hydroxyapatite concentration that the brand describes as micro-fine. Its best-cited trial found it not statistically inferior to a 1450 ppm fluoride paste over 18 months, most of its cited research discloses Dr. Wolff funding or employee authors, and one trial it cites found no significant difference on its primary outcome. The open questions are a particle size, an RDA number, and how a 2011 nano-hydroxyapatite paper relates to a paste marketed as micro. If you want a fluoride-free paste with its concentration on the page, Bioniq is one of the clearer choices; talk it through with your dentist, and ignore the Trustpilot rating with the same name.
Keep your toothpaste. Add a measured dose.
Minvelle is a nano-hydroxyapatite gum with 5.7 mg per piece printed on the box, xylitol-sweetened and fluoride-free. One piece a day, chewed for at least 20 minutes, 18 pieces per box, as an add-on to brushing, never a replacement.
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