Test it in your practice. Then earn on every box you recommend.
Minvelle is a nano-hydroxyapatite chewing gum: 5.7 mg nano-HAp per 1.9 g piece, xylitol-based, plant-based gum base (chicle and mastic, with a touch of spruce), one piece a day, positioned strictly as a complement to fluoride brushing, never a replacement. The full formula with per-piece weights and the independent lab assessment are public on our transparency page.
Here is the deal. We send up to 5 free sample kits so you can judge it yourself. If it holds up, your practice gets a personal code. Your patients get 10% off their first one-time order with it, and your practice earns 10% on every order that uses the code, paid monthly, no minimum, no cap. Subscriptions are never discounted, for anyone, so the code never turns into a price war. Practice pricing for chairside resale is available on request.
Up to 5 sample kits, shipped free within the EU and to US practices.
A personal practice code, 10% off for your patients' first one-time order.
10% on every order with your code, paid monthly. No minimum, no cap, no exclusivity.
Full partner conditions (PDF). Prefer email? Write to kooperation@minvelle.com with your name, credential, practice name and shipping address.
Max, founder
Same gum, different question.
A pharmacist, a hygienist, a dentist and a student ask us four different things about this product. Here is the honest answer to each one, with the source attached, so you can check it instead of taking a brand's word for it.
I am a pharmacist in the UK or the EU and I want to recommend a hydroxyapatite gum. What can I say over the counter?
Stay inside the authorised wordings. For a sugar-free chewing gum in the EU they come from the Annex to Regulation (EU) No 432/2012: "Sugar-free chewing gum contributes to the maintenance of tooth mineralization", "Sugar-free chewing gum contributes to the neutralisation of plaque acids" and "Sugar-free chewing gum contributes to the reduction of oral dryness". The condition attached to the first two is that the customer is told the beneficial effect is obtained with chewing, for at least 20 minutes, after eating or drinking. Those are the wordings available to any sugar-free gum, Minvelle included, and only with that 20-minute information alongside. In Great Britain the register of authorised claims is maintained separately from the EU one, so check the GB register before you print anything.
What we do not say, and what you should not say on our behalf: that Minvelle remineralises teeth, prevents cavities, or treats a condition. There is no finished-product clinical trial on this gum. We are not going to pretend there is.
What we do publish, so you can answer a customer without phoning us: 5.7 mg of nano-hydroxyapatite per 1.9 g piece (0.30% of piece weight), particles rod-shaped, 200 nm long and 20 to 50 nm wide per supplier specification, all 14 ingredients with their per-piece weights, and the independent safety assessment of the formula. It contains egg shell powder, so it carries an egg allergen and is not vegan. Sugar-free, fluoride-free, one piece a day, 18 pieces in a box. Everything above is on the transparency page.
I am a dental hygienist. What is the actual evidence for hydroxyapatite in a chewing gum?
The paper everyone cites is Limeback H, Enax J, Meyer F, Clinical Evidence of Biomimetic Hydroxyapatite in Oral Care Products for Reducing Dentin Hypersensitivity: An Updated Systematic Review and Meta-Analysis, Biomimetics (Basel) 2023;8(1):23, PMID 36648809. Read it, it is open access. Read it with two caveats in front of you.
First, scope. It covers 44 clinical trials, the endpoint is dentin hypersensitivity rather than caries, and nearly all of the included products are toothpastes. Exactly one included trial is a chewing gum, and that row is graded LOW quality of evidence in the review's own summary table. One low-graded trial is not a body of evidence for gum.
Second, the conflict of interest, which the paper states itself: two of the three authors are employees of Dr. Kurt Wolff GmbH & Co. KG, a company that sells hydroxyapatite oral care. That does not make the review wrong. It does mean you read it as an interested party's review, not a neutral one.
So the review is a reasonable starting point on the ingredient. It is not evidence about our gum, and we never present it as such.
I am a dentist. Where does hydroxyapatite gum sit against fluoride, and what is the honest evidence hierarchy?
Fluoride is the standard and we are not arguing with it. The Cochrane review of fluoride toothpaste (Walsh, 2019, CD007868) covers 96 studies, 85 of them with 48,804 randomised participants, and finds high-certainty caries reductions for 1,000–1,500 ppm fluoride versus placebo. There is nothing remotely that size on the hydroxyapatite side, and nothing at all at that size for gum.
The one clinical gum trial is Porciani PF, Chazine M, Grandini S, J Clin Dent 2014;25(2):32-6, PMID 25122980. Double blind, 107 enrolled and 100 completed, 50 per group. The test gum carried 12 mg calcium hydroxyapatite plus 97 mg dicalcium phosphate dihydrate per 1.4 g stick, and subjects chewed two sticks three times a day for two weeks.
The placebo arm is the part usually left out of the marketing. At two weeks the test group's index reductions were 54% tactile, 66% air blast, 49% cold water. The placebo gum group reached 30%, 25% and 31% on the same indexes, and those reductions were themselves statistically significant (p < 0.01). The between-group differences were significant, but chewing anything for two weeks moves these numbers, and the trial cannot separate the hydroxyapatite from the dicalcium phosphate because both were in the same stick.
Where that leaves Minvelle: a different product at a different dose, roughly 72 mg of hydroxyapatite a day in that trial versus 5.7 mg once a day here, on an endpoint we make no claim about. We position the gum as an adjunct to fluoride brushing and to xylitol exposure between meals. It is not a therapy and not a fluoride replacement, and if a patient asks you for the option with formal professional endorsement behind it, that answer is fluoride. Minvelle carries no ADA Seal of Acceptance and no dental association endorsement anywhere. We have not applied for one.
I am a dental student or researcher. Where is the underlying data, and can I reuse it?
Three sources, all free, none of them behind an email form.
The transparency page holds all 14 ingredients with per-piece weights, the piece geometry, the independent safety assessment of the formula and the raw-material analysis, both as PDFs. One redaction, disclosed on the page: our manufacturer's identity is blacked out. Lab, report numbers, batch number, dates and results are untouched.
The Hydroxyapatite Gum Database records what every hydroxyapatite gum brand we could find publishes about dose, particle size, ingredient amounts and lab data, including us, and marks where a brand publishes nothing.
The same database as a raw CSV, on GitHub at github.com/oehlusbert/hydroxyapatite-gum-database, file data/gum-spec-database.csv. Every row carries an as_of date and a source URL, and the commit history is the changelog. Reuse it, cite it, correct it. If a figure is wrong, open an issue and we will fix it in public.
If you are running a study and want product, write to kooperation@minvelle.com. We will send boxes and we will not ask for a favourable result.
I practise in the UK, the US or Australia. Can you ship, and does any of this apply where I am?
Shipping: the United Kingdom, the United States, Australia, Canada and New Zealand are all in the current shipping list, alongside most of the EU. Checkout is the live authority on the list. Partner program sample kits go out free of charge (up to 5 per practice) within the EU and to US practices; for anywhere else, ask at kooperation@minvelle.com and we will tell you the cost before you commit to anything.
Regulatory: every claim wording on this page is an EU wording under Regulation (EU) No 432/2012. It is not an FDA, TGA, MHRA or GB register statement, and we do not translate it into local claims we have not earned. Minvelle is sold as a food, not as a therapeutic good, a medical device or a drug, and it is not registered as any of those in any market. If your local rules are stricter than the EU wordings above, your local rules win.