BioMin toothpaste review 2026: bioactive glass, no HAp
Product Review

BioMin toothpaste review 2026: bioactive glass, no HAp

BioMin F, BioMin C and BioMin F for Kids come from a Queen Mary University of London spin-out and work with bioactive glass, not hydroxyapatite. This review covers what is in each tube, the 2026 stock situation in the brand's own words, the company records, the studies and where to buy.

M
Max, Founder of Minvelle
Updated September 2026 · Last reviewed: 26 September 2026 · 22 min read

Disclosure: this review is by Minvelle. We make a remineralizing gum with nano-hydroxyapatite, which is a different kind of product from a toothpaste. Every BioMin fact below comes from BioMin's pages, its stockists, public registers or PubMed, each checked on 26 September 2026.

Before you buy

Glass or apatite: know which one you are buying

BioMin is a bioactive-glass toothpaste. Minvelle is a chewing gum with a stated nano-hydroxyapatite dose: 5.7 mg per piece, for between brushings. Different tools, different jobs.

Read the Minvelle formula

30-day refund on unopened boxes

The short version

BioMin is a British toothpaste built on bioactive glass, not hydroxyapatite. BioMin F releases calcium, phosphate and fluoride (530 ppm), which the brand says form fluorapatite on the tooth; BioMin C is the fluoride-free chloride version. On 26 September 2026 the brand says BioMin "will be returning", and its stockists list it as sold out.

There is no hydroxyapatite in any BioMin tube, and that is by design: BioMin's own FAQ presents nano-hydroxyapatite as a different technology. The company behind it, BioMin Technologies Limited, is on the UK register with Queen Mary University of London as a 25 to 50 percent shareholder. The resolved studies it cites test relief from what their authors call "dentine hypersensitivity"; none of them measured cavities.

Four things to know before you pay. The UK stockist Twice Daily has "no confirmed restock date". The Australian distributor gives a "guesstimate" of November 2026 to February 2027 for BioMin F. In the US the glass is sold as Dr.Collins BioMin Restore. And for one of the trials the brand cites, we set two public records side by side in Part 5, without comment.

If you searched "biomin toothpaste" or "biomin f", you probably want three answers: what it is, whether you can still buy it, and whether the science holds. This review takes them in that order and quotes the documents rather than summarising them. If you arrived here comparing remineralizing toothpastes in general, our guide to the best hydroxyapatite toothpaste covers the other main technology; BioMin is its own category and we treat it that way.

At a glance

BioMin F, C, Kids and Minvelle, side by side

What's checked BioMin F BioMin C BioMin F for Kids Minvelle gum
Format Toothpaste, 75 ml tube (18 ml travel tube) Toothpaste, 75 ml tube Toothpaste, strawberry, age 3+ Chewing gum, 18 pieces per box
Active Fluoro calcium phospho silicate (bioactive glass) Chloro calcium phospho silicate (bioactive glass) Fluoro calcium phospho silicate (bioactive glass) Nano-hydroxyapatite
Hydroxyapatite in the tube None None None 5.7 mg per 1.9 g piece
Fluoride 530 ppm None 530 ppm None
SLS Yes Yes Yes Not applicable (not a toothpaste)
Stock on 26 Sep 2026 Sold out at stockists checked Sold out; AU distributor not taking orders Sold out at stockists checked In stock at minvelle.com
Price £11.99 for 75 ml at Twice Daily (UK) No live UK price found No live UK price found €24.99 per box
Study on the product Several trials on BioMin F (see Part 5) None among the resolved studies None among the resolved studies No clinical trial on the gum; batch certificate published

Swipe sideways on mobile. BioMin data from biomin.co.uk product pages and FAQ; stock and price from Twice Daily and LAZARK Medical; all checked 26 September 2026. "Resolved" means we found the paper in PubMed.

Part 1

Is BioMin in stock? The brand and its distributors, in their words

This is the question most people are really asking in 2026, so it comes first. We did not phone anyone and we are not guessing. Below is exactly what BioMin and two of its sellers published on their own pages when we checked them on 26 September 2026.

Who says it Where Exact words, 26 Sep 2026
BioMin Technologies Limited biomin.co.uk homepage "BioMin will be returning. Join our mailing list to receive official updates." and "Back In Stock Soon! Thanks for your Patience. Due to regulatory updates, supply is temporarily disrupted across many stockists. We're working hard to resolve this and will share updates soon, thank you for your patience and continued support."
Twice Daily (UK stockist) BioMin F product page "Temporary Stock Update. BioMin toothpaste is currently out of stock. Due to regulatory updates, manufacturing and supply have been temporarily disrupted across the UK and other markets. BioMin is working to resolve this as quickly as possible, but at present, we do not have a confirmed restock date." Single tube, 4-pack and 8-pack all shown as sold out.
LAZARK Medical (exclusive distributor, Australia and New Zealand) biomintoothpaste.com.au shop page "Dear loyal BioMin customers, due to global manufacturing delays, all BioMin Variants are SOLD OUT. We are awaiting approval to recommence manufacturing" and "A temporary purchase limit of 5 tubes per customer applies until normal supply resumes."

Quotes copied from each page on 26 September 2026. Pages change; check the source before you order.

LAZARK adds its own timeline, which it calls a "guesstimate" and marks as such: "Below dates are guesstimates only." For BioMin F and BioMin F for Kids it gives November to February 2027. For BioMin C it writes "New stock is guesstimate until H1 2027" and "We are not taking orders at this point." It also invites customers to "place an order now to ensure priority supply once products are replenished", and says that "Mixed orders will be held until all stock arrives."

What the three sources agree on: the product is out of stock in more than one country, and the reason given is regulatory or manufacturing, not demand. The brand and Twice Daily both use the phrase "regulatory updates"; LAZARK says it is "awaiting approval to recommence manufacturing". None of the three names the regulator, the country or the specific approval involved. We do not either, because we have nothing beyond their words to go on.

What this means where you live

UK: BioMin's stockist page lists Upbeat Care, Twice Daily, Growing Smiles and Amazon. Twice Daily, the one whose page we could read in full, showed every BioMin F option as sold out and gave no restock date. If you see a UK listing with stock, it is worth checking the seller against BioMin's stockist page before you pay.

Australia and New Zealand: LAZARK Medical is named by BioMin as the exclusive distributor for both countries. Its page invites priority orders ahead of its November to February 2027 estimate for BioMin F and BioMin F for Kids, is not taking orders for BioMin C, and limits each customer to five tubes once supply returns.

US: BioMin is not sold under its own name. Dr.Collins sells a fluoride-free version called Dr.Collins BioMin Restore Toothpaste, with the chloride glass as its active. On 26 September 2026 Dr.Collins' product catalogue listed it with prices (see Part 7). We did not place an order, so we cannot tell you shipping times.

Canada and Europe: BioMin lists Tradeo International for Canada, and named stockists in Ireland, Germany, Italy, Belgium and the Netherlands, the Czech Republic, Hungary, Poland, Slovakia, Bulgaria and the Baltic states. We did not check stock at each of them. Given the brand's own homepage notice, assume supply is limited until BioMin says otherwise.

If you rely on BioMin and are running low, the practical step is a conversation with your dentist about a stop-gap. The options depend on what you used it for. Our guide to Sensodyne alternatives maps the main mechanisms, including bioactive glass, arginine, potassium nitrate and stannous fluoride, by what each label actually contains.

Part 2

What BioMin is: bioactive glass, not hydroxyapatite

The single most important fact about BioMin is also the most misunderstood: there is no hydroxyapatite in the tube. The active ingredient is a glass. It is made by melting a mix of silica, phosphate, calcium and either fluoride or chloride, then quenching and milling it. BioMin's science page puts it this way: the glass is "melted at 1450 Celsius and quenched in cold water to produce glass frit, which is then milled". When the fine glass particles meet saliva, they dissolve slowly and release ions.

What those ions do next is where apatite comes in. In BioMin's words, from the BioMin F product page:

"BioMin ® F produces calcium, phosphate and fluoride ions. These combine to form fluorapatite that helps strengthen and protect the tooth surface."

And for the fluoride-free version, from the BioMin C product page: "Formulated with chloride instead of fluoride, a hydroxyapatite layer provides long lasting and fast acting protection." The US seller Dr.Collins describes the same chloride glass in the plainest terms we found:

"BioMin (Chloro Calcium Phospho Silicate): Active ingredient which adheres to the tooth upon brushing and slowly dissolves [in] saliva to release calcium and phosphate which precipitate on the tooth surfaces as hydroxycarbonated apatite (same as the natural tooth)."

So an apatite mineral is the result, formed on the tooth from ions the glass releases. It is not the ingredient. That is the opposite of a hydroxyapatite toothpaste, where the apatite is added ready-made as particles. Both routes aim to put calcium phosphate mineral where enamel or exposed dentine needs it. They get there differently.

BioMin's own view of nano-hydroxyapatite

BioMin does not blur the two. Its FAQ has a question titled "What is a nano-Hydroxyapatite toothpaste and how is BioMin different?" and answers it directly:

"Nano-Hydroxyapatite (HAP) has been around for a number of years most recently sold on its fluoride free benefits. It works by acting as an inert block to acids, so when under acid attack from food or drink, the HAP dissolves in preference to your enamel... BioMin ® works differently to provide a slow release of ions that create a higher level of clinically proven protection... BioMin F contains low levels of fluoride that form fluorapatite which dissolves at a pH of <4.0, HAP at a pH of 5.0, so is much more acid resistant."

That is BioMin's description of a competing technology, and we report it as their claim. It is a fair summary of one line of thinking; researchers who work on hydroxyapatite describe its mechanism in broader terms, and our comparison of nano-HAp, CPP-ACP and fluoride sets the main remineralizing approaches out side by side. BioMin's science page also lists "Nano-hap Hydroxyapatite" as one of three named competing technologies, next to NovaMin and Pro-Argin, that it benchmarks BioMin F against. On BioMin's own terms, then, it is not a hydroxyapatite product and does not want to be one.

Particle size and concentration

BioMin does not publish a particle size in nanometres. Its FAQ says "the particles are very small (one tenth of the width of a human hair)", and its science page says the particles "are engineered to be 60% smaller than those found in NovaMin™ products." On common estimates of hair width, one tenth of a hair falls in the micrometre range, not the nanometre range. That is not a criticism; the glass works by dissolving and releasing ions, so nano-scale size is not the point of the design.

The percentage of glass in the retail tube is not stated on BioMin's product pages or FAQ. The trial summaries BioMin itself hosts consistently describe the tested paste as "5% fluorocalcium phosphosilicate (BioMin® F)", and the resolved trials in Part 5 use the same figure. So 5 percent is the figure used in the studies, but BioMin does not state it as the formulation of the tube you buy.

Why only 530 ppm fluoride

BioMin F and BioMin F for Kids both state: "Fluoride concentration is 530ppm." Typical adult fluoride toothpaste sits around 1,450 ppm, so BioMin F carries about a third of that. The brand says this is deliberate. Its science page says BioMin F "challenges conventional fluoride concentrations with just 530ppm, releasing it slowly", and describes a study in which "BioMin ® F with 900ppm soluble fluoride had similar apatite formation rates as BioMin ® F alone, indicating the extra fluoride was washed away". It quotes co-founder Professor Robert Hill: "Simply increasing the amount of fluoride is not the solution, it invariably just goes to waste."

The science page does not name that 900 ppm study, so we cannot check it. What we can say: fluoride is the most studied anti-cavity ingredient in toothpaste, and the question of whether 530 ppm released slowly matches a standard-strength paste for cavity prevention is one the studies we resolved do not test. If your dentist has told you that you have a high cavity risk, show them the 530 ppm figure before switching. Our explainer on nano-hydroxyapatite vs fluoride covers how the evidence for each is built.

The glass chemistry behind it

The underlying science is real and peer-reviewed. A 2010 paper in Acta Biomaterialia by Brauer, Karpukhina, O'Donnell, Law and Hill (PMID 20132911), from Robert Hill's research group, studied fluoride-containing bioactive glasses in simulated body fluid. Its abstract opens: "Bioactive glasses are able to bond to bone through formation of carbonated hydroxyapatite in body fluids, and fluoride-releasing bioactive glasses are of interest for both orthopaedic and, in particular, dental applications for caries inhibition." This is a materials-science study of glass behaviour, not a trial of the finished toothpaste, and BioMin cites it on its science page in that role.

The glasses are also patented. Google Patents' copy of the official records shows US9168272B2, "Bioactive glass composition", granted on 27 October 2015, which describes glasses "comprising SiO2, P2O5 and a fluoride" for uses "including dental applications such as toothpaste". The chloride family, "Chlorine-containing silicate glasses and glass ceramics", includes WO2014154874 and the granted European patent EP2978383 B1, with a UK priority date of 28 March 2013. Both name Robert Hill as inventor and Queen Mary and Westfield College as assignee.

Remember this

Glass, not apatite

Every BioMin tube uses a bioactive glass as its active. The glass releases calcium, phosphate and, in BioMin F, fluoride. BioMin says these form fluorapatite or a hydroxyapatite layer on the tooth. There is no hydroxyapatite added to the tube.

Remember this

Out of stock, in their words

On 26 September 2026 the brand said BioMin "will be returning" and cited "regulatory updates". The UK stockist Twice Daily had no confirmed restock date. The Australian distributor estimated November 2026 to February 2027 for BioMin F.

Remember this

Read the records yourself

BioMin has a real university pedigree and an independent systematic review behind the glass it uses. Some trials it cites include authors connected to the company or its manufacturer. Part 5 shows the public records next to each other so you can judge.

Two new flavours land in December

Calm Matcha and Warm Cinnamon. Join the first-dibs list and pick yours before anyone else.

Part 3

BioMin F, BioMin C and Kids: every tube, mapped

BioMin makes three toothpastes under its own name. In the US, the chloride glass is sold by a partner under the partner's brand. There is also a fluoride version with a US drug label that is not currently on sale. Here is the full map, from BioMin's product pages, Dr.Collins' catalogue and DailyMed, all checked on 26 September 2026.

Product Fluoride Active glass Where
BioMin F Yes, 530 ppm Fluoro calcium phospho silicate UK, EU, Australia and New Zealand under the BioMin name
BioMin C No Chloro calcium phospho silicate UK, EU, Australia and New Zealand under the BioMin name
BioMin F for Kids Yes, 530 ppm (same as BioMin F) Fluoro calcium phospho silicate Same markets; strawberry flavour, age 3 and up
Dr.Collins BioMin Restore Toothpaste No Chloro calcium phospho silicate, per Dr.Collins US only, sold by Dr.Collins, Inc., 3.5 oz tube
BioMin Restore Plus Yes, sodium fluoride, 530 μg/g Not named on its FDA label US drug label on DailyMed since 2020; not in Dr.Collins' catalogue on 26 Sep 2026

Sources: biomin.co.uk/products pages, drcollins.com product catalogue, DailyMed setid a47a410f-3a68-2024-e053-2995a90acdaf; checked 26 September 2026.

The full ingredient lists

BioMin publishes complete ingredient lists. Here they are verbatim.

BioMin F: "Glycerin, PEG 400, Silica, Fluoro Calcium Phospho Silicate, Sodium Lauryl Sulphate, Titanium Dioxide, Aroma, Carbomer, and Potassium Acesulfame. Fluoride concentration is 530ppm."
BioMin C: "Glycerin, Silica, PEG 400, Chloro Calcium Phospho Silicate, Sodium Lauryl Sulphate, Titanium Dioxide, Aroma, Carbomer, and Potassium Acesulfame. Fluoride free formulation."
BioMin F for Kids: "Glycerin, PEG 400, Silica, Fluoro Calcium Phospho Silicate, Sodium Lauryl Sulphate, Titanium Dioxide, Aroma, Carbomer, and Potassium Acesulfame. Fluoride concentration is 530ppm."

Three details are worth noticing. First, the Kids list is identical to the adult BioMin F list, and BioMin's FAQ confirms it "contains the same levels of active ingredients as the mint flavoured BioMin F"; only the flavour differs. Second, all three UK formulas contain sodium lauryl sulphate (SLS), the common foaming agent. The US Dr.Collins version swaps SLS for cocamidopropyl betaine and sodium methyl cocoyl taurate, so if you avoid SLS, the US formula differs from the UK one in a way that matters to you. Third, every version contains titanium dioxide as a colouring agent. BioMin C's page also repeats the list once with the typo "Cluoro"; it is the same chloro glass, not a second ingredient.

There is no potassium nitrate, arginine, stannous fluoride or strontium in any BioMin paste. BioMin attributes its effect on exposed dentine to the glass particles blocking the tiny tubules in dentine, not to a nerve-calming ingredient.

Abrasivity and how to brush

BioMin's FAQ gives one abrasivity number: "BioMin ® F is classed as a low abrasive toothpaste, with an RDA value of 68." It adds that low abrasion is "essential" for a paste aimed at exposed dentine. That figure is self-reported on the FAQ; we did not find a lab certificate for it. For context, it is the only RDA figure BioMin publishes, and it applies to BioMin F.

The brushing instructions on the BioMin F page are unusually specific. It describes a six-step routine and ends: "After 2 minutes swirl the foamy toothpaste around your mouth for 30 seconds and spit out the excess in the sink", followed by "Do not rinse!" and "Do not eat or drink for at least 30 minutes after brushing or it will undo much of your good work." The logic follows from the mechanism: the glass needs time in contact with saliva to release ions. If you usually rinse or have breakfast straight after brushing, this is the habit BioMin asks you to change.

Sizes and labels

Retail tubes are 75 ml at the stockists we checked, and the BioMin F page mentions an 18 ml travel tube: "Our flagship formulation in an 18ml travel friendly tube to take wherever you go". The US Dr.Collins tube is 3.5 oz. All three UK product pages carry the bullets "Vegan and Halal" and "Not Tested on Animals"; the pages do not name a certifying body for either claim, so treat them as BioMin's own statements.

Part 4

Who makes BioMin: a Queen Mary University spin-out

BioMin's about page says: "BioMin Technologies Limited was established to commercialise the award-winning research conducted at Queen Mary University of London and Imperial College, London." Many brands tell a university story. This one is on the public register.

Companies House record Detail, checked 26 Sep 2026
Company BIOMIN TECHNOLOGIES LIMITED, company number 09122826
Incorporated 9 July 2014; status Active
Registered office Qmb Innovation Centre, New Road, London, E1 2AX
Nature of business SIC 32500, manufacture of medical and dental instruments and supplies
Person with significant control Queen Mary University of London, notified 1 July 2016: ownership of shares and of voting rights, each "More than 25% but not more than 50%"
Filings Accounts made up to 31 July 2025, next due 30 April 2027; confirmation statement dated 9 July 2026

Source: find-and-update.company-information.service.gov.uk/company/09122826, overview, officers and persons with significant control pages.

The shareholding is the important line. It is a statutory filing, independent of BioMin's marketing, and it shows that Queen Mary University of London holds between a quarter and a half of the company. The brand's domain, biomin.co.uk, was registered on 17 April 2015, about nine months after the company was incorporated, according to the Nominet registry record.

The people

The register lists these directors among others. Professor Robert Hill has been a director since 26 November 2014, with a correspondence address at the Dental Institute on Mile End Road. BioMin's Australian distributor describes him as "Director and Chief Scientific Officer" who "currently holds the Chair of Physical Sciences in the Dental Institute at Queen Mary University, London. Formerly Professor of Biomaterials at Imperial College." He is the named inventor on both patent families and a senior author on the 2010 glass-chemistry paper above. Anthony Julian Lyell Beare has also been a director since 26 November 2014. Alec John Hilton has been a director since 6 April 2022, and BioMin's own site notice names him as "Chief Executive Officer".

One corporate director is listed too: James Kent Consolidated Limited (company number 07052616), appointed 9 July 2019, with a registered address on Fountain Street, Fenton, Stoke-on-Trent. BioMin's own site notice gives the same Fountain Street, Fenton, Stoke-on-Trent address for BioMin Technologies Limited. We note the match of addresses and draw no further conclusion from it.

Other appointments on the register include Barry Clare (director since 18 February 2025), Dr Adam Charles Daykin (director since 28 May 2020) and Sunil Cajaten Attavar (director since 5 March 2026). One former director, Dr David Geoffrey Gillam, appears again in Part 5.

Part 5

Does BioMin work? The studies, and the records beside them

BioMin's clinical studies page lists ten evidence summaries. We searched each one in PubMed, the US National Library of Medicine's index of medical research. Five resolved to a PubMed record. Five did not. Here are the five that did, with what each tested and what its PubMed record says about conflicts of interest.

One term first. Almost all of these trials measure what their authors call "dentine hypersensitivity" or "dentin hypersensitivity", abbreviated DH. The BMC Oral Health trial defines it as "a sharp toothache that influences a patients' oral health-related quality of life." In practice it is short, sharp pain from exposed dentine when it meets cold air, water or a probe. We use DH below.

Study (PMID) What it tested Result, per the abstract Conflict statement in PubMed
Arshad, Zaidi, Farooqui. BMC Oral Health 2021 (34615511) 140 adults with DH, 4 groups: BioMin F (FCPS), Pro-Argin, 8% strontium acetate, sodium fluoride paste; triple-blinded; 6 weeks Pro-Argin and strontium acetate gave the fastest relief at one minute; FCPS "showed the highest reduction in DH" on two measures at six weeks "The authors declare that they have no competing interests (financial and non-financial) related to the article."
Patel, Shettar, Thakur, Gillam, Kamala. J Oral Rehabil 2019 (31233629) 75 patients with DH, 3 groups: 5% fluorocalcium phosphosilicate, 8% arginine with calcium carbonate, placebo; 1 month "Group A showed a better reduction of DH than the other two groups." No conflict-of-interest statement in the PubMed record
Ashwini, Swatika, Kamala. Contemp Clin Dent 2018 (30166822) 60 adults with DH, 3 groups: 5% fluoro calcium phosphosilicate, 5% calcium sodium phosphosilicate (NovaMin), standard fluoride paste; 60 days FCPS "showed a higher degree of effectiveness in reducing DH, followed by calcium sodium phosphosilicate then standard fluoride dentifrices" "There are no conflicts of interest."
Petrović, Galić, Seifert, Lešić, Smolić. Biomedicines 2023 (37509631) Systematic review of 7 randomised trials, 2018 to 2022, of bioactive-glass products for DH, with Cochrane risk-of-bias assessment FCPS "may be the most effective long-term treatment option"; "FCPS at a concentration of 5%" was effective in adults "The authors declare no conflict of interest." Funded by a Croatian Ministry of Science and Education institutional grant
Brauer, Karpukhina, O'Donnell, Law, Hill. Acta Biomater 2010 (20132911) Laboratory study of fluoride-containing bioactive glasses in simulated body fluid Glass design changes degradation, pH and apatite formation; not a toothpaste trial No conflict statement field in the PubMed record

Sources: PubMed records for each PMID, retrieved 26 September 2026. FCPS = fluoro calcium phosphosilicate, the BioMin F glass.

Read together, the resolved evidence says something fairly specific. Two independent groups, a Pakistani university team in 2021 and a Croatian systematic review in 2023, both declaring no competing interests, found that the fluoro calcium phosphosilicate glass in BioMin F performed well for DH over weeks, not minutes. The 2021 trial also found that two competitors gave faster relief at the one-minute mark. That is a balanced, credible picture for the glass as a treatment for exposed dentine.

What the resolved studies do not cover is just as important. None of the five measured cavities. None tested BioMin C by name. None tested BioMin F for Kids. BioMin's pages describe the pastes as strengthening and protecting teeth, and the chemistry supports the idea of mineral forming on the tooth, but the clinical trials we could find are about DH. If you want a paste for cavity prevention specifically, that gap is worth knowing.

The five summaries we could not find in PubMed

These five are hosted on BioMin's clinical studies page. We could not find a PubMed record for any of them on 26 September 2026. Most appear in journals that PubMed does not index, which does not make them wrong; it means we could not read them through the same index we used for the others, so we do not rely on them.

They are: Reddy and colleagues in the Journal of Dr NTR University of Health Sciences; Gautam and Halwai in the International Journal of Scientific Research; Hussain, Jan and Behal in the International Journal of Medical and Biomedical Studies; a paper in Acta Scientific Dental Sciences; and Mishra, Suryawanshi and Thaper in the International Journal of Community Medicine and Public Health, the newest entry on BioMin's page.

BioMin's homepage also carries a banner that reads "Reduced Sensitivity by up to 90.7% in just 1 month", citing "Patel et al., Journal of Conservative Dentistry, 2019. A randomised, double-blind clinical trial." We could not find a PubMed record matching that citation. The indexed 2019 Patel paper we did find (PMID 31233629, above) is in the Journal of Oral Rehabilitation, and its abstract does not report a 90.7 percent figure. We list the banner as BioMin states it and leave the figure there.

Two records, side by side

For the 2019 Journal of Oral Rehabilitation trial, which BioMin cites on its page about "clinically-proven-superior-management-dentine-hypersensitivity", two public records exist. We set them next to each other with their dates. We add nothing to them.

UK Companies House, officers of BioMin Technologies Limited (checked 26 Sep 2026) PubMed record for PMID 31233629 (checked 26 Sep 2026)
"GILLAM, David Geoffrey, Dr". Role: Director. Appointed 13 May 2015. Resigned 28 February 2026. Correspondence address: Room E204, Queens' Building, Mile End Road, London E1 4NS. Published 2019, J Oral Rehabil 46(12):1121-1126. Author "Gillam D", affiliation as listed: "Oral Bioengineering, Institute of Dentistry, Barts and London School of Medicine and Dentistry, Queen Mary University, London, UK." Conflict-of-interest statement: none present in the PubMed record.

We read the PubMed record, not the journal's full-text PDF, so a declaration printed only in the full text would not appear here.

The manufacturer link, as the distributor page states it

A second pair of records concerns co-author D. N. Kamala, who appears on both the 2019 and the 2018 trials above.

LAZARK Medical, BioMin's Australian distributor, about page (checked 26 Sep 2026) PubMed records for PMIDs 30166822 and 31233629 (checked 26 Sep 2026)
Under the heading "Manufacturing": "Group Pharmaceutical Limited was founded in 1980 and has become a world leading contract manufacturer of dental care products..." and "Group Pharmaceuticals has gained an expertise in the formulation and production of dentifrices (toothpastes) containing bioactive glasses." PMID 30166822 (2018): author "Kamala DN", affiliation "Research Coordinator, Group Pharmaceuticals Limited, Bengaluru, Karnataka, India." Conflict statement: "There are no conflicts of interest." PMID 31233629 (2019): author "Kamala DN", affiliation "Group Pharmaceuticals Limited, Bengaluru, Karnataka, India."

Attribution: the description of Group Pharmaceuticals is the distributor's wording, not ours.

For how we read industry-linked and independent studies across the hydroxyapatite category, see our review of nano-hydroxyapatite safety evidence; the same reading rules apply here.

Part 6

Is BioMin safe and approved? Regulators, recalls and reviews

UK and EU: a medical device, per BioMin

BioMin describes its pastes as a medical device rather than a cosmetic. Its about page says: "We are an approved class IIb medical device under ISO 13485" and "Both of these toothpastes have undergone examination by the National Standards Authority of Ireland and have received CE certification for the treatment of dentine hypersensitivity under ISO 13485 as recognised by the CE mark on our pack." The National Standards Authority of Ireland (NSAI) is a real EU notified body for medical devices. The UK has no consumer-searchable product register for devices comparable to the US databases, so we could not look this up product by product. We report it as BioMin's statement.

US: one drug label, and a claim on the seller's page

DailyMed, the US National Library of Medicine's database of drug labels, has exactly one BioMin-family record: "BIOMIN RESTORE PLUS (SODIUM FLUORIDE) PASTE, DENTIFRICE [DRCOLLINS, INC.]", published on 20 May 2020. Its purpose line reads "Anticavity & Sensitivity Relief", and its active ingredient is "Sodium Fluoride. (Fluoride concentration is 530μg/g by weight.)" The bioactive glass is not named on that label. On 26 September 2026 this Restore Plus product did not appear in Dr.Collins' product catalogue.

The product Dr.Collins does list, the fluoride-free BioMin Restore, has no DailyMed label. That is normal: in the US, fluoride toothpastes are sold under the FDA's over-the-counter monograph rules, and fluoride-free pastes are regulated as cosmetics, which do not need a drug label. The Dr.Collins product page for the fluoride-free Restore opens with the line "FDA Approved for Tooth Sensitivity". We quote it as Dr.Collins' wording and set it next to the two DailyMed facts above: one drug label, for a fluoride product not in the current catalogue, and none for the product on the page.

BioMin's about page also says "we are also one of the few products approved by the TGA and US FDA". We could not reach the Australian TGA register on 26 September 2026 to check the TGA part, so we make no statement about it either way.

Recalls and lawsuits

We searched the openFDA drug enforcement database for a recalling firm named BioMin: no matches on 26 September 2026. We searched CourtListener's federal court archive for "BioMin" with toothpaste: no results. On the specific records we checked, there is no US recall and no federal lawsuit. We did not find any other legal action to report.

What buyers say

We could read one independent review platform in full. On ProductReview.com.au, the Australian consumer review site, the BioMin F listing showed 4.9 out of 5 from 642 reviews, 98 percent positive, with a taste score of 4.7, and a 2026 award badge, on 26 September 2026. Reviews quoted on the page include "Love using Biomin F for its enamel-protective active ingredient and inclusion of fluoride" and "Recommended by our dentist, we have been using Biomin F for the past few years now." The most common reservation we saw was price: "The only downside is that it is too pricey." That is a strong, consistent record from real buyers, and it matches the distributor's own claim that BioMin is "ProductReview.com.au's no.1 dental brand".

Part 7

BioMin price, stockists and returns

BioMin does not sell on biomin.co.uk. Every "Buy Now" button on the brand's site leads to a stockist or a marketplace, and the site shows no prices. So the prices below come from sellers, not from BioMin.

Where Product Price seen on 26 Sep 2026
Twice Daily (UK) BioMin F, 75 ml £11.99 per tube; 4-pack and 8-pack listed; all sold out
Dr.Collins (US) BioMin Restore Toothpaste, fluoride-free, 3.5 oz $10.99 for 1, $18.99 for 2, $28.99 for 3, $37.99 for 4, $52.99 for 6
LAZARK Medical (Australia, New Zealand) All BioMin variants No per-tube price readable; every variant marked sold out

Prices change and may exclude shipping. Check the seller before ordering.

We found no subscription option for BioMin anywhere, neither on the brand site nor at any stockist we checked; the only "subscribe" option on biomin.co.uk is a newsletter. Because BioMin has no checkout, it also has no returns page of its own. Returns are handled by whichever seller you buy from.

For US buyers, Dr.Collins' refund policy is worth reading before you order. It says: "DrCollins.com. offers a 14 day return policy from the date of purchase for any UNOPENED product... We reserve the right to charge a 20% return fee for any non-defective unopened products returned... Products that have been OPENED cannot be resold and as such are only offered a 50% credit", and "DrCollins.com does NOT accept 'I DON'T LIKE IT' returns." In short, a toothpaste you try and do not like is not refundable in full there.

The full official stockist list

BioMin's stockist page, checked 26 September 2026, names these sellers by country. United Kingdom: Upbeat Care, Twice Daily, Growing Smiles, Amazon. Australia and New Zealand: LAZARK Medical, as exclusive distributor. Belgium and the Netherlands: Corim Dental, Tandwinkel. Bulgaria: Complete Dental Solutions. Canada: Tradeo International. Czech Republic, Hungary, Poland and Slovakia: Profimed. Estonia, Latvia and Lithuania: Oralmeda, plus Suutervis in Estonia. Germany: Dent-o-Care. Ireland: Burbel. Italy: Sorriso Deciso. United States: Dr.Collins, under the Dr.Collins BioMin Restore name.

Part 8

What BioMin does well, and what no toothpaste can do

It would be easy to read the records in Part 5 and stop there. That would be unfair to a brand that, on the documents, does several things better than most in this category.

The pedigree is real and filed. Queen Mary University of London's 25 to 50 percent shareholding is a statutory record, not a marketing line. The lead scientist is a named inventor on granted patents and published the underlying glass chemistry in a peer-reviewed journal years before the product reached shelves.

BioMin is precise about what it is. Its FAQ explains in plain words that it is not a nano-hydroxyapatite product and how it differs. Plenty of brands blur their category to borrow a trend; BioMin does the opposite and says so on its own site.

The label is complete. Full ingredient lists, a stated fluoride level of 530 ppm for both F versions, a stated RDA of 68 for BioMin F, and specific brushing instructions. You know what you are putting in your mouth.

There is independent evidence for the glass. The 2023 systematic review from Osijek and the 2021 trial from Karachi both declared no competing interests and both found the BioMin F glass performed well for DH over weeks.

Buyers like it. 4.9 out of 5 from 642 reviews on ProductReview.com.au is a large, consistent sample.

The record is clean where we looked. No FDA recall and no federal lawsuit on the searches we ran.

What it cannot do

No toothpaste repairs a cavity once it has formed; that needs a dentist. No toothpaste, BioMin included, whitens teeth by forming mineral. And the resolved trials for BioMin are about DH, not cavities, so any claim that BioMin prevents decay better than a standard fluoride paste is not something the studies we could resolve show. The same honesty applies to us: there is no clinical trial on the finished Minvelle gum. We publish the dose and the batch certificate, and we say plainly what the gum has and has not been tested for.

Part 9

BioMin or nano-hydroxyapatite: which fits you

These are different tools, and you do not have to pick a side. Here is how they differ on the points people actually weigh.

If you want fluoride, but less of it: BioMin F is one of very few pastes that combines a mineral-forming active with a low, stated fluoride level (530 ppm). A nano-hydroxyapatite paste is usually fluoride-free, and a standard fluoride paste usually carries around 1,450 ppm.

If you want no fluoride at all: BioMin C and the US Dr.Collins Restore are fluoride-free and use the chloride glass. Nano-hydroxyapatite toothpastes are the other main fluoride-free route; our ranking of fluoride-free toothpastes compares them by what each label discloses, and our Boka toothpaste review and Apagard toothpaste review look at two of the best known in detail.

If exposed dentine is your main issue: the resolved trial evidence for BioMin F is specifically about DH, and it is decent. That is the use case where the glass has the most published support among the studies we could check. Your dentist can tell you whether that is what you have.

If you want to know the dose: BioMin states its fluoride level but not the percentage of glass in the tube; the trials used 5 percent. Hydroxyapatite brands vary widely here, and most do not state an amount at all.

If the stock-out is the problem: the brand's own estimate for BioMin F in Australia is late 2026 to early 2027, and the UK has no date. Whatever you choose meanwhile, choose it with your dentist, not from a marketplace listing.

Where a gum fits: Minvelle is a chewing gum and does not replace brushing. It is sugar-free and made for between brushings: 5.7 mg of nano-hydroxyapatite and 817 mg of xylitol per 1.9 g piece, one piece a day, chewed for at least 20 minutes. You can brush with BioMin, or anything else, and still use it.

BioMin and Minvelle, side by side

Fact BioMin F (biomin.co.uk, 26 Sep 2026) Minvelle
Nano-HAp per tube or piece None (active is bioactive glass) 5.7 mg per 1.9 g piece, printed on the box
Active and fluoride Fluoro calcium phospho silicate glass; 530 ppm fluoride (BioMin C: chloride glass, fluoride-free) Nano-hydroxyapatite plus 817 mg xylitol per piece; fluoride-free
What is published Full ingredient list, fluoride ppm, RDA 68, patents, trials on BioMin F; no glass percentage on the product page, particle size as an analogy only Dose, particle size and batch certificate
Price, pack and directions £11.99 for 75 ml at Twice Daily (sold out on 26 Sep 2026); brush, spit, do not rinse, no food or drink for 30 minutes €24.99 for 18 pieces, 1 piece a day, at least 20 minutes

Minvelle is for people who want a written per-piece nano-hydroxyapatite dose to chew between brushings; if you want a low-fluoride or fluoride-free toothpaste built on bioactive glass from a university spin-out, with independent trial support for exposed dentine, BioMin F or BioMin C is a considered choice for brushing once it is back in stock.

See the dose on the box →

Minvelle prints the dose on the box: 5.7 mg nano-hydroxyapatite per piece. See the gum.

Who should buy BioMin, and who should wait

A good fit: adults who want a mineral-forming paste with some fluoride but less than a standard paste; people whose dentist has pointed to exposed dentine, where the BioMin F glass has its best published evidence; and anyone who prefers a brand whose university backing is on the public register.

Think twice or wait: anyone who needs to buy today, given the stock notices; people avoiding SLS in the UK formulas; families where a dentist has recommended a specific fluoride strength for a child, since BioMin F for Kids carries 530 ppm; and US buyers who want to try a paste and return it if they dislike it, given the Dr.Collins returns terms.

Summary

BioMin toothpaste, in one paragraph

BioMin is a genuine, university-backed toothpaste range that uses bioactive glass instead of hydroxyapatite: BioMin F with 530 ppm fluoride, BioMin C without fluoride, and BioMin F for Kids with the same formula as BioMin F in strawberry. Queen Mary University of London is a registered 25 to 50 percent shareholder of the company, the glasses are patented, and independent research supports the BioMin F glass for DH over weeks. The brand is clear that it is not a nano-hydroxyapatite product. On 26 September 2026 it is out of stock at the stockists we checked, for reasons the brand calls "regulatory updates", with an Australian estimate of November 2026 to February 2027 for BioMin F. Two public records about one cited trial are shown side by side in Part 5 for you to read.

Facts checked on 26 September 2026 from the sources below; if BioMin or its stockists change their pages, tell us and we will update this review.

Glossary

Bioactive glass: A glass made from silica, calcium, phosphate and other oxides that slowly dissolves in body fluids and releases ions. In toothpaste, those ions can form an apatite mineral on the tooth.

Fluoro calcium phospho silicate (FCPS): The fluoride-containing bioactive glass in BioMin F and BioMin F for Kids. The chloride version in BioMin C is chloro calcium phospho silicate.

Fluorapatite: A form of tooth mineral in which fluoride takes the place of the hydroxyl group in hydroxyapatite. BioMin says it is more acid resistant than hydroxyapatite.

ppm: Parts per million. 530 ppm fluoride means 530 mg of fluoride per kilogram of toothpaste, the same as the 530 μg/g on the US label.

RDA: Relative dentine abrasivity, a lab score for how abrasive a toothpaste is. BioMin states 68 for BioMin F.

Class IIb medical device: A European risk class for medical devices that needs assessment by a notified body. BioMin says its pastes are certified in this class through the NSAI.

Questions, answered

The things people actually ask

Is BioMin toothpaste discontinued?

Not according to the brand. On 26 September 2026 the BioMin homepage said "BioMin will be returning" and that "due to regulatory updates, supply is temporarily disrupted across many stockists." The UK stockist Twice Daily listed it as out of stock with no confirmed restock date. The Australian and New Zealand distributor, LAZARK Medical, listed every BioMin variant as sold out and gave its own "guesstimate" of November to February 2027 for BioMin F and BioMin F for Kids, and the first half of 2027 for BioMin C.

Does BioMin contain hydroxyapatite?

No. BioMin's active ingredient is a bioactive glass: fluoro calcium phospho silicate in BioMin F and BioMin F for Kids, chloro calcium phospho silicate in BioMin C. The glass dissolves slowly and releases calcium and phosphate (plus fluoride in the F versions). BioMin says these ions form fluorapatite (BioMin F) or a hydroxyapatite coating (BioMin C) on the tooth, so an apatite mineral is the result, not the ingredient. BioMin's own FAQ describes nano-hydroxyapatite as a different technology.

How much fluoride is in BioMin F?

BioMin F and BioMin F for Kids both state "Fluoride concentration is 530ppm." That is about a third of the roughly 1,450 ppm found in typical adult fluoride toothpaste. BioMin says the low level is deliberate because the glass releases fluoride slowly. BioMin C contains no fluoride.

Is BioMin F for Kids suitable for children?

BioMin labels BioMin F for Kids for age 3 years and up, in strawberry flavour, and its FAQ says it "contains the same levels of active ingredients as the mint flavoured BioMin F", so 530 ppm fluoride. Fluoride levels for children are something to agree with your dentist, especially if your child has a high cavity risk.

Where can I buy BioMin in the UK, Australia or the US?

BioMin does not sell on its own website. Its stockist page lists Upbeat Care, Twice Daily, Growing Smiles and Amazon for the UK, LAZARK Medical as exclusive distributor for Australia and New Zealand, and Dr.Collins for the US, where the product is sold as Dr.Collins BioMin Restore. On 26 September 2026 the UK and Australian stockists we checked showed BioMin as out of stock.

What is the difference between BioMin F and BioMin C?

BioMin F uses a fluoride-containing glass and contains 530 ppm fluoride; BioMin says it forms fluorapatite. BioMin C uses a chloride-containing glass and is fluoride-free; BioMin says it forms a hydroxyapatite coating. Otherwise the UK ingredient lists are nearly identical, and both contain sodium lauryl sulphate.

Medical disclaimer: this article is educational and is no medical advice. It does not diagnose, treat or replace professional care. Talk to your dentist before changing your oral-care routine, and before changing the fluoride level you or your children use. Product formulations, listings and ingredient lists change over time; always check the current label and consult your dentist about your individual enamel and gum health.

Sources
  1. Arshad S, Zaidi SJA, Farooqui WA. Comparative efficacy of BioMin-F, Colgate Sensitive Pro-relief and Sensodyne Rapid Action in relieving dentin hypersensitivity: a randomized controlled trial. BMC Oral Health 2021;21:498. PMID 34615511
  2. Patel VR, Shettar L, Thakur S, Gillam D, Kamala DN. A randomised clinical trial on the efficacy of 5% fluorocalcium phosphosilicate-containing novel bioactive glass toothpaste. J Oral Rehabil 2019;46(12):1121-1126. PMID 31233629
  3. Ashwini S, Swatika K, Kamala DN. Comparative Evaluation of Desensitizing Efficacy of Dentifrice Containing 5% Fluoro Calcium Phosphosilicate versus 5% Calcium Sodium Phosphosilicate: A Randomized Controlled Clinical Trial. Contemp Clin Dent 2018;9:330-336. PMID 30166822
  4. Petrović D, Galić D, Seifert D, Lešić N, Smolić M. Evaluation of Bioactive Glass Treatment for Dentin Hypersensitivity: A Systematic Review. Biomedicines 2023;11(7):1992. PMID 37509631
  5. Brauer DS, Karpukhina N, O'Donnell MD, Law RV, Hill RG. Fluoride-containing bioactive glasses: effect of glass design and structure on degradation, pH and apatite formation in simulated body fluid. Acta Biomaterialia 2010. PMID 20132911
  6. UK Companies House, BIOMIN TECHNOLOGIES LIMITED (09122826): overview, officers and persons with significant control, checked 26 September 2026
  7. DailyMed label, BioMin Restore Plus (sodium fluoride) paste, dentifrice, labeler Dr.Collins, Inc., setid a47a410f
  8. US9168272B2, Bioactive glass composition, granted 27 October 2015 (Google Patents)
  9. WO2014154874, Chlorine-containing silicate glasses and glass ceramics (Google Patents)
  10. openFDA drug enforcement query for recalling firm BioMin: no matches, 26 September 2026
  11. BioMin FAQ and other BioMin pages at biomin.co.uk, quoted verbatim above and checked on the review date: homepage, about, products (BioMin F, BioMin C, BioMin F for Kids), FAQ, the science, clinical studies, stockists, site notice. Stockist pages: Twice Daily BioMin F listing; LAZARK Medical (biomintoothpaste.com.au) shop and about pages; Dr.Collins BioMin Restore product page, product catalogue and refund policy. ProductReview.com.au BioMin F listing. Nominet RDAP record for biomin.co.uk. CourtListener search for BioMin: no results on the review date
M

About the author

Max, Founder of Minvelle, builds an Austrian oral-care brand around one rule: publish the numbers, cite the sources, and say plainly what a product cannot do. He is not a dentist and does not play one online, which is why every article on this blog ends by pointing you to yours. The full formula behind Minvelle, every ingredient and dose, is public on the transparency page.

Documents over adjectives. This review set out to answer what people type about BioMin, from "what is it" to "is it discontinued" to "does it work", and to let the records do the talking. What came out is a university spin-out with a real, filed shareholding, patented glass chemistry, a complete label and strong buyer ratings, whose pastes are out of stock for regulatory reasons the brand has not yet detailed. BioMin could make this article better easily: state the percentage of glass in each tube, name the regulatory step behind the stock-out, and publish a restock date. We would welcome writing that update. All findings reflect the listed pages and records as checked on 26 September 2026; pages change, and the sources are there so you can re-check every claim.

Between brushings

A remineralizing gum with the dose in writing

Keep brushing with the paste you like. Minvelle is for between brushings: 5.7 mg of nano-hydroxyapatite per piece, printed on the box, xylitol-sweetened and fluoride-free, one piece a day chewed for at least 20 minutes. 18 pieces per box, batch certificate published.

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